What's new
Apr 12 2011 Blast and ClustalW services were restarted.
Mar 14 2011 Due to the effects of disaster to nuclear power plants, eastern Japan is now under a rolling blackout. This website will be affected accordingly. Sorry for the inconvenience.
    All services will be unavailable irregularly.
    ARSA, Blast, ClustalW and Gib services are unavailable for the time being.
Bioinformatics web service
We publish the REST and the SOAP interface that can be used from several program languages for aiming standardization in bioinformatics and the improvement of the interoperability of the biological information resource.
There are 18 services and 124 methods in Web API for Biology.


Web services in the world
Available services
Data retrieve and keyword search
Service nameOverview
DDBJ Retrieve DDBJ entry
GetEntry Database search and entry retrieve by accession number against DDBJ and other biological molecular database.
ARSA Keyword search system against over 20 life sciences databases developed by DDBJ
Sequence search and analysis
Service nameOverview
Blast Finds regions of similarity between biological sequences developed by NCBI
ClustalW Multiple sequence alignment program for DNA or proteins developed by EBI
Mafft Multiple alignment program for amino acid or nucleotide sequeces developed in Kyoto Univ and Kyushu Univ
VecScreen A system for quickly identifying segments of a nucleic acid sequence that may be of vector origin
PhylogeneticTree Generate phylogenetic from phylip format data.
DDBJ original system
Service nameOverview
Gib Genome Information Broker (GIB) is the comprehensive data repository of complete microbial genomes in the public domain.
Gtop Genome To Protein (GTOP) is a database which summarizes analysis results against coding sequences identified by various genome projects.
GTPS Gene Trek in Prokaryote Space (GTPS) is a database which is re-annotated ORFs against microorganism genome data in DDBJ database.
GIBV Genome Information Broker for Viruses (GIB-V) is a complete virus genome data repository extracted from DDBJ database.
GIBIS Genome Information Broker for Insertion Sequence (GIBIS) is a database containing whole bacterial IS data obtained by extracting IS region from publicized nucleotide sequences of DDBJ.
SPS Splicing Profile based Score (SPS) is a new method to compare two amino acid sequences.
Other public database system
Service nameOverview
TxSearch A retrieval system for Taxonomy Database which was unified by DDBJ, GenBank and EMBL
Ensembl Ensembl is a joint project between EMBL - EBI and the Sanger Institute to develop a software system which produces and maintains automatic annotation on selected eukaryotic genomes.
NCBIGenomeAnnotation NCBI Genome annotation is a summary of NCBI genome database.
Getting result which is called asynchronously
Service nameOverview
RequestManager A service for getting result which is called asynchronously

Workflow Navigation System
You can use several bioinformatics service with common web interface. This system provides not only the result of service but also the next services.
Links for bioinformatics


[Reference] Yeondae Kwon, Yasumasa Shigemoto, Yoshikazu Kuwana and Hideaki Sugawara "Web API for biology with a workflow navigation system" Nucleic Acids Research, 2009, Vol. 37, No. suppl_2 W11-W16
[Reference] Sugawara H, Miyazaki S. Biological SOAP servers and web services provided by the public sequence data bank. Nucleic Acids Res. 2003 Jul 1;31(13):3836-9
"Web API for Biology" was supported in 2003-2005 by the project of "Research and Development of Biological Portal Site of the New Generation" and continues developing in the BIRD project.
Last Updated: Nov 01, 2010